Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 16/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909050 | 0.94 | S1PR2 (0.77) | S1PR2TSHRCMA1ALOX15 | |
| SCHEMBL23914696 | 0.92 | S1PR2 (0.64) | S1PR2TSHR | |
| SCHEMBL23915077 | 0.90 | S1PR2 (0.83) | S1PR2TSHRCMA1ALOX15 | |
| SCHEMBL23908889 | 0.89 | S1PR2 (0.93) | S1PR2TSHRCMA1ALOX15 | |
| SCHEMBL23909020 | 0.88 | S1PR2 (0.78) | S1PR2 | |
| SCHEMBL23914695 | 0.87 | S1PR2 (0.79) | S1PR2TSHRCMA1ALOX15 | |
| SCHEMBL23908887 | 0.87 | S1PR2 (0.94) | S1PR2TSHRCMA1ALOX15 | |
| SCHEMBL23915019 | 0.87 | S1PR2 (0.77) | S1PR2TSHRCMA1ALOX15 | |
| SCHEMBL23908951 | 0.86 | S1PR2 (1.00) | S1PR2TSHRCMA1ALOX15 | |
| SCHEMBL23908925 | 0.86 | S1PR2 (1.00) | S1PR2TSHRCMA1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |