Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 17/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966894 | 0.94 | S1PR2 (0.80) | S1PR2KCNH2RXFP1 | |
| SCHEMBL23908854 | 0.89 | S1PR2 (1.00) | S1PR2KCNH2 | |
| SCHEMBL23908778 | 0.88 | S1PR2 (0.80) | S1PR2KCNH2 | |
| SCHEMBL23915495 | 0.88 | S1PR2 (0.88) | S1PR2KCNH2 | |
| SCHEMBL23908888 | 0.87 | S1PR2 (0.81) | S1PR2KCNH2 | |
| SCHEMBL23908836 | 0.87 | S1PR2 (0.80) | S1PR2KCNH2 | |
| SCHEMBL23908949 | 0.86 | S1PR2 (0.77) | S1PR2KCNH2RXFP1 | |
| SCHEMBL23915497 | 0.84 | S1PR2 (0.81) | S1PR2KCNH2 | |
| SCHEMBL23966899 | 0.84 | S1PR2 (0.81) | S1PR2KCNH2 | |
| SCHEMBL23908903 | 0.83 | S1PR2 (0.79) | S1PR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |