Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 19/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908763 | 0.92 | S1PR2 (0.47) | S1PR2 | |
| SCHEMBL23908812 | 0.88 | S1PR2 (0.57) | S1PR2 | |
| SCHEMBL23915593 | 0.86 | S1PR2 (0.49) | S1PR2 | |
| SCHEMBL23908804 | 0.83 | S1PR2 (0.46) | S1PR2 | |
| SCHEMBL23908883 | 0.78 | S1PR2 (0.56) | S1PR2 | |
| SCHEMBL23915485 | 0.76 | S1PR2 (0.48) | S1PR2 | |
| SCHEMBL23908815 | 0.73 | S1PR2 (0.62) | S1PR2 | |
| SCHEMBL23909015 | 0.71 | S1PR2 (0.47) | S1PR2 | |
| SCHEMBL23909004 | 0.71 | S1PR2 (0.63) | S1PR2 | |
| SCHEMBL23908997 | 0.70 | S1PR2 (0.47) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |