Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 11/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966605 | 0.89 | S1PR2 (0.55) | S1PR2KDM4EHSD17B10NPSR1MAPT | |
| SCHEMBL23908736 | 0.86 | S1PR2 (0.61) | S1PR2KDM4EHSD17B10NPSR1MAPT | |
| SCHEMBL23908826 | 0.86 | S1PR2 (0.58) | S1PR2KDM4EHSD17B10NPSR1MAPT | |
| SCHEMBL23908894 | 0.85 | S1PR2 (0.58) | S1PR2KDM4EHSD17B10NPSR1MAPT | |
| SCHEMBL23966898 | 0.85 | S1PR2 (0.52) | S1PR2KDM4EHSD17B10POLB | |
| SCHEMBL23909046 | 0.85 | S1PR2 (0.61) | S1PR2KDM4EHSD17B10NPSR1MAPT | |
| SCHEMBL23908871 | 0.84 | S1PR2 (0.60) | S1PR2KDM4EHSD17B10NPSR1MAPT | |
| SCHEMBL23908790 | 0.84 | S1PR2 (0.61) | S1PR2KDM4EHSD17B10MAPTTP53 | |
| SCHEMBL23914585 | 0.84 | S1PR2 (0.68) | S1PR2KDM4EHSD17B10NPSR1MAPT | |
| SCHEMBL23908816 | 0.84 | S1PR2 (0.58) | S1PR2KDM4EHSD17B10NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |