Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 16/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908795 | 0.90 | S1PR2 (0.66) | S1PR2KCNH2 | |
| SCHEMBL23909105 | 0.86 | S1PR2 (0.54) | S1PR2KCNH2 | |
| SCHEMBL23908832 | 0.80 | S1PR2 (0.64) | S1PR2MAPT | |
| SCHEMBL23966899 | 0.79 | S1PR2 (0.81) | S1PR2KCNH2MAPT | |
| SCHEMBL23966884 | 0.78 | S1PR2 (0.54) | S1PR2RECQL | |
| SCHEMBL23914486 | 0.76 | S1PR2 (0.53) | S1PR2RECQL | |
| SCHEMBL23908728 | 0.76 | S1PR2 (0.67) | S1PR2 | |
| SCHEMBL23908818 | 0.69 | S1PR2 (0.94) | S1PR2KCNH2 | |
| SCHEMBL23908854 | 0.69 | S1PR2 (1.00) | S1PR2KCNH2 | |
| SCHEMBL28380866 | 0.68 | S1PR2 (0.75) | S1PR2KCNH2MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |