Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 14/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909006 | 1.00 | S1PR2 (0.60) | S1PR2POLBCYP2C19 | |
| SCHEMBL23908814 | 0.89 | S1PR2 (0.74) | S1PR2 | |
| SCHEMBL23908805 | 0.88 | S1PR2 (0.69) | S1PR2 | |
| SCHEMBL23908824 | 0.87 | S1PR2 (0.73) | S1PR2POLBCYP2C19 | |
| SCHEMBL23914738 | 0.86 | S1PR2 (0.73) | S1PR2 | |
| SCHEMBL23915332 | 0.85 | S1PR2 (0.58) | S1PR2POLBCYP2C19 | |
| SCHEMBL23915670 | 0.84 | S1PR2 (0.59) | S1PR2POLB | |
| SCHEMBL23908865 | 0.82 | S1PR2 (0.63) | S1PR2POLB | |
| SCHEMBL23908738 | 0.81 | S1PR2 (0.78) | S1PR2 | |
| SCHEMBL23966612 | 0.80 | S1PR2 (0.58) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |