Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966621 | 0.90 | S1PR2 (0.56) | S1PR2MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL23908761 | 0.87 | S1PR2 (0.61) | S1PR2MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL23908898 | 0.86 | S1PR2 (0.59) | S1PR2MEN1KMT2ACXCR3TP53 | |
| SCHEMBL23908946 | 0.85 | S1PR2 (0.62) | S1PR2MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL23909027 | 0.84 | S1PR2 (0.62) | S1PR2MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL23966649 | 0.83 | S1PR2 (0.59) | S1PR2MEN1KMT2ATP53 | |
| SCHEMBL23908991 | 0.83 | S1PR2 (0.59) | S1PR2MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL23966656 | 0.82 | S1PR2 (0.50) | S1PR2MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL23909089 | 0.82 | S1PR2 (0.78) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23966618 | 0.81 | S1PR2 (0.52) | S1PR2MEN1KMT2ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |