Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 15/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23913408 | 0.90 | S1PR2 (0.79) | S1PR2AKR1B1 | |
| SCHEMBL23908737 | 0.89 | S1PR2 (0.66) | S1PR2TP53POLBAKR1B1 | |
| SCHEMBL23966887 | 0.88 | S1PR2 (0.81) | S1PR2TP53POLBAKR1B1 | |
| SCHEMBL23908746 | 0.87 | S1PR2 (0.74) | S1PR2AKR1B1 | |
| SCHEMBL23915665 | 0.86 | S1PR2 (0.62) | S1PR2TP53POLBAKR1B1 | |
| SCHEMBL23915334 | 0.83 | S1PR2 (0.61) | S1PR2TP53POLB | |
| SCHEMBL23908738 | 0.82 | S1PR2 (0.78) | S1PR2 | |
| SCHEMBL23914738 | 0.79 | S1PR2 (0.73) | S1PR2AKR1B1 | |
| SCHEMBL23908951 | 0.79 | S1PR2 (1.00) | S1PR2 | |
| SCHEMBL23908982 | 0.77 | S1PR2 (1.00) | S1PR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |