⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12259629 | 1.00 | — | — | |
| SCHEMBL5728624 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2392943 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL2392957 | 0.96 | — | — | |
| SCHEMBL442109 | 0.78 | — | — | |
| SCHEMBL24599887 | 0.75 | — | — | |
| Hydrogen Sulfide SCHEMBL8742082 | 0.75 | — | — | |
| SCHEMBL341359 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL3033584 | 0.75 | — | — | |
| SCHEMBL5946162 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580710-B2 | Pesticidal active mixtures comprising aminothiazoline compounds | BASF SE (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20110224075-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | BASF SE (DE) | 2011-09-15 | — | — | US | disclosed |
| CN-101506166-B | Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane compounds | BASF SE | 2011-08-24 | — | — | CN | disclosed |
| CN-101980607-A | Pesticidal active mixtures comprising aminothiazoline compounds | BASF SE | 2011-02-23 | — | — | CN | disclosed |
| CN-101679336-A | Substituted amino-thiourea compounds for combating animal pests | BASF SE | 2010-03-24 | — | — | CN | disclosed |
| CN-101621928-A | Pesticidal active mixtures comprising aminothiazoline compounds | BASF SE | 2010-01-06 | — | — | CN | disclosed |
| CN-101578278-A | Substituted 1- (azolin-2-yl) -amino-1, 2-heterocyclyl-ethane compounds for combating pests | BASF SE (DE) | 2009-11-11 | — | — | CN | disclosed |
| CN-101506166-A | Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane compounds | BASF SE (DE) | 2009-08-12 | — | — | CN | disclosed |
| EP-0515121-B1 | Process for preparing intermediates to nizatidine and related compounds | LILLY CO ELI (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-0960880-A1 | Process for preparing intermediates to nizatidine and related compounds | ELI LILLY AND COMPANY (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5457206-A | Reacting a 4-hydroxy-4-chloromethyl-2-(aminomethyl)thiazoline with an alkali metal compound in an inert solvents to dechlorination | ELI LILLY AND COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| US-5334725-A | 2-aminomethyl-4-exomethylenethiazoline epoxides | ELI LILLY AND COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0515121-A1 | Process for preparing intermediates to nizatidine and related compounds | ELI LILLY AND COMPANY (US) | 1992-11-25 | — | — | EP | disclosed |