Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 11/20 | 0.60 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908858 | 0.89 | S1PR2 (0.75) | S1PR2GRIN1GRIN2B | |
| SCHEMBL23914638 | 0.85 | S1PR2 (0.80) | S1PR2RHEB | |
| SCHEMBL23908851 | 0.85 | S1PR2 (0.64) | S1PR2IDH1RHEB | |
| SCHEMBL23908801 | 0.82 | S1PR2 (0.67) | S1PR2RHEBGRIN1GRIN2B | |
| SCHEMBL23908734 | 0.80 | S1PR2 (0.69) | S1PR2IDH1RHEB | |
| SCHEMBL23908887 | 0.79 | S1PR2 (0.94) | S1PR2 | |
| SCHEMBL23909124 | 0.78 | S1PR2 (0.56) | S1PR2RHEBPDE5A | |
| SCHEMBL23914694 | 0.76 | S1PR2 (0.76) | S1PR2 | |
| SCHEMBL23908740 | 0.74 | S1PR2 (0.67) | S1PR2 | |
| SCHEMBL23908861 | 0.73 | S1PR2 (0.76) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |