Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 12/20 | 0.52 |
| ▸ | RBP4 | P02753 | 5/20 | 0.35 |
| ▸ | TTR | P02766 | 5/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908922 | 0.89 | S1PR2 (0.59) | S1PR2RBP4TTREGLN1 | |
| SCHEMBL23914685 | 0.87 | S1PR2 (0.54) | S1PR2RBP4TTR | |
| SCHEMBL23908933 | 0.77 | S1PR2 (0.58) | S1PR2 | |
| SCHEMBL23909004 | 0.77 | S1PR2 (0.63) | S1PR2RBP4TTREGLN1 | |
| SCHEMBL23914687 | 0.76 | S1PR2 (0.52) | S1PR2 | |
| SCHEMBL23915325 | 0.76 | S1PR2 (0.58) | S1PR2RBP4TTRCACNA1H | |
| SCHEMBL23908800 | 0.69 | S1PR2 (1.00) | S1PR2 | |
| SCHEMBL23908833 | 0.66 | S1PR2 (0.44) | S1PR2 | |
| SCHEMBL23913415 | 0.66 | S1PR2 (0.94) | S1PR2 | |
| SCHEMBL23908815 | 0.65 | S1PR2 (0.62) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |