Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 8/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908998 | 0.89 | S1PR2 (0.83) | S1PR2AKR1B1 | |
| SCHEMBL23908866 | 0.89 | S1PR2 (0.68) | S1PR2POLBATMMAPTTP53 | |
| SCHEMBL23915668 | 0.86 | S1PR2 (0.66) | S1PR2POLBATMMAPTTP53 | |
| SCHEMBL23915328 | 0.86 | S1PR2 (0.68) | S1PR2POLBATMAKR1B1 | |
| SCHEMBL23908732 | 0.83 | S1PR2 (0.71) | S1PR2POLBMAPTTP53 | |
| SCHEMBL23966890 | 0.83 | S1PR2 (0.62) | S1PR2POLBATMMAPTAKR1B1 | |
| SCHEMBL23909034 | 0.81 | S1PR2 (0.81) | S1PR2AKR1B1 | |
| SCHEMBL23908760 | 0.80 | S1PR2 (0.67) | S1PR2POLBATMMAPTTP53 | |
| SCHEMBL23909082 | 0.79 | S1PR2 (0.57) | S1PR2POLBAKR1B1 | |
| SCHEMBL23908887 | 0.79 | S1PR2 (0.94) | S1PR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |