SCHEMBL23967978

CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCN(C)C)OC)N(C)C(=O)[C@@H](NC(=O)C(C(C)C)N(C)C(C)C)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CYP3A4	P08684	1/20	0.43

▸	SSTR2	P30874	2/20	0.42

▸	FOLH1	Q04609	3/20	0.37

▸	TTR	P02766	2/20	0.35

▸	REN	P00797	1/20	0.35

▸	CTSD	P07339	6/20	0.35

▸	CTSE	P14091	6/20	0.35

▸	BACE1	P56817	4/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19144617	1.00	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL20075905	1.00	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL13838247	1.00	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL2734901	1.00	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL10285897	1.00	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL20133986	0.96	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL15047595	0.95	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL2759936	0.95	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL20157568	0.94	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN
SCHEMBL10305563	0.94	CYP3A4 (0.43)	CYP3A4SSTR2FOLH1TTRREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3903812-A1	ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS	Agensys, Inc. (US)	2021-11-03	—	—	EP	disclosed