SCHEMBL2396856

SCHEMBL2396856

NC1(N)CCCCC1(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28380030 0.97
SCHEMBL3191516 0.97
SCHEMBL11443360 0.90
Phosphonic Acid SCHEMBL14603435 0.83
SCHEMBL5448313 0.73
SCHEMBL6418913 0.73
SCHEMBL1766154 0.73 TSHR (0.33)
SCHEMBL6061678 0.73
SCHEMBL10975471 0.73
SCHEMBL23358998 0.70 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023178531-A1 ALBUMIN NANOPARTICLE CONJUGATED WITH INDOCYANINE GREEN AND OXALIPLATIN, PREPARATION THEREFOR AND USE THEREOF 苏州大学 2023-09-28 WO disclosed
CN-108129518-A A kind of preparation method of Miboplatin 昆明贵研药业有限公司 2018-06-08 CN disclosed
CN-103705383-B A kind of oxaliplatin freeze-dried powder SHANDONG NEW TIME PHARMACEUTICAL Co.,Ltd. (CN) 2015-08-05 CN disclosed
CN-104650179-A Novel platinum prodrug capable of being cracked by lysosomal enzyme UNIV SOUTHEAST 2015-05-27 CN disclosed
CN-103705383-A Oxaliplatin lyophilized powder injection SHANGDONG NEW TIME PHARM PROD 2014-04-09 CN disclosed
CN-101612146-B Oxaliplatin medicament composition, preparation method thereof SHANDONG LUOXIN PHARMACY STOCK 2012-07-25 CN disclosed
CN-102603804-A Novel platinum complex, preparation method and applications of platinum complex Kunming guiyan pharmaceutical co ltd 2012-07-25 CN disclosed
US-8012463-B2 Coordination complex of diaminocyclohexaneplatinum(II) with block copolymer containing poly(carboxylic acid) segment and antitumor agent comprising the same TOUDAI TLO, LTD. (JP) 2011-09-06 US disclosed
CN-101899067-A Preparation method of meter platinum UNIV SOUTHEAST 2010-12-01 CN disclosed
EP-1695991-B1 COORDINATION COMPLEX OF DIAMINOCYCLOHEXANEPLATINUM(II) WITH BLOCK COPOLYMER CONTAINING POLY(CARBOXYLIC ACID) SEGMENT AND ANTITUMOR AGENT COMPRISING THE SAME TOUDAI TLO LTD (JP) 2010-02-17 EP disclosed
CN-101612146-A A kind of oxaliplatin medicament composition and preparation method thereof, and the synthetic method of crude drug oxaliplatin SHANDONG LUOXIN PHARMACY STOCK 2009-12-30 CN disclosed
CN-100457185-C Coordination complex of diaminocyclohexanepolatinum (II) and block copolymer containing polycarboxylic acid segment, and antitumor agent thereof TOUDAI TLO LTD (JP) 2009-02-04 CN disclosed
US-20070148125-A1 Coordination complex of diaminocyclohexaneplatinum(II) with block copolymer containing poly(carboxylic acid) segment and antitumor agent comprising the same TOUDAI TLO, LTD. (JP) 2007-06-28 US disclosed
CN-1890295-A Coordination complex of diaminocyclohexanepolatinum (II) and block copolymer containing polycarboxylic acid segment, and antitumor agent thereof TOUDAI TLO LTD (JP) 2007-01-03 CN disclosed
EP-1695991-A1 COORDINATION COMPLEX OF DIAMINOCYCLOHEXANEPLATINUM(II) WITH BLOCK COPOLYMER CONTAINING POLY(CARBOXYLIC ACID) SEGMENT AND ANTITUMOR AGENT COMPRISING THE SAME TOUDAI TLO, Ltd. (JP) 2006-08-30 EP disclosed