Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.81 |
| ▸ | DPP8 | Q6V1X1 | 17/20 | 0.81 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995580 | 0.94 | DPP4 (0.71) | DPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL2399082 | 0.90 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL2396924 | 0.85 | DPP4 (0.78) | DPP4DPP8DPP9 | |
| SCHEMBL3404667 | 0.85 | DPP4 (0.78) | DPP4DPP8DPP9 | |
| SCHEMBL8007575 | 0.83 | DPP4 (0.89) | DPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL2398411 | 0.82 | DPP4 (0.79) | DPP4DPP8 | |
| SCHEMBL13525327 | 0.76 | DPP4 (0.75) | DPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL5649111 | 0.76 | DPP4 (0.66) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL18281110 | 0.75 | DPP4 (0.73) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5068240 | 0.75 | DPP4 (0.73) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022096-B2 | Pyrrolidine derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-09-20 | — | — | US | disclosed |
| US-20090227569-A1 | PYRROLIDINE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227569-A1 | PYRROLIDINE DERIVATIVES | DPP4, DPP7, DPP3 | DPP4 1/4885DPP8 4/4885DPP9 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.