Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 5/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.31 |
| ▸ | CDK2 | P24941 | 5/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.31 |
| ▸ | CCNC | P24863 | 2/20 | 0.31 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 2/20 | 0.31 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.31 |
| ▸ | DMPK | Q09013 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.31 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17823262 | 1.00 | F2 (0.32) | F2IKBKBNR1H4CDC7CCNE1 | |
| SCHEMBL17823321 | 0.89 | F2 (0.31) | F2 | |
| SCHEMBL22176326 | 0.87 | NR1H4 (0.32) | F2IKBKBNR1H4MEN1CYP2D6 | |
| SCHEMBL22176004 | 0.85 | NR1H4 (0.31) | F2NR1H4MEN1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL22164192 | 0.84 | NR1H4 (0.31) | NR1H4MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL17823250 | 0.84 | PDE10A (0.38) | CHRNB2CHRNA4PDE10A | |
| SCHEMBL17827741 | 0.81 | TSHR (0.42) | KMT2A | |
| SCHEMBL2737966 | 0.81 | NPC1 (0.35) | F2IKBKBNR1H4MEN1CYP2D6 | |
| SCHEMBL17823248 | 0.81 | NPC1 (0.35) | F2IKBKBNR1H4MEN1CYP2D6 | |
| SCHEMBL2737909 | 0.81 | HRH4 (0.33) | NR1H4MEN1CYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903788-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2021-11-03 | — | — | EP | disclosed |