Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003016 | 0.95 | ESR1 (0.57) | ESR1ESR2ALDH1A1GAAKMT2A | |
| SCHEMBL16395145 | 0.95 | ESR1 (0.57) | ESR1ESR2ALDH1A1GAAKMT2A | |
| SCHEMBL22003013 | 0.91 | ESR1 (0.67) | ESR1ESR2ALDH1A1GAAHTT | |
| SCHEMBL22003017 | 0.91 | ESR1 (0.67) | ESR1ESR2ALDH1A1GAAHTT | |
| SCHEMBL12590933 | 0.88 | ESR1 (0.50) | ESR1ESR2ALDH1A1GAAHTT | |
| SCHEMBL14580094 | 0.88 | ESR1 (0.50) | ESR1ESR2ALDH1A1HTTKMT2A | |
| SCHEMBL14064751 | 0.87 | ESR1 (0.49) | ESR1ESR2HSD11B1ALDH1A1GAA | |
| SCHEMBL12021689 | 0.86 | ESR1 (0.56) | ESR1ESR2HSD11B1ALDH1A1GAA | |
| SCHEMBL22651381 | 0.86 | ESR1 (0.56) | ESR1ESR2HSD11B1ALDH1A1GAA | |
| SCHEMBL16394592 | 0.86 | ESR1 (0.58) | ESR1ESR2ALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388468-B1 | AROMATIC POLYCARBONATE OLIGOMER SOLID | HONSHU CHEMICAL IND (JP) | 2021-11-03 | — | — | EP | disclosed |