Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.69 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.69 |
| ▸ | PIK3CB | P42338 | 16/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.60 |
| ▸ | PLK4 | O00444 | 1/20 | 0.60 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.60 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.60 |
| ▸ | GAK | O14976 | 1/20 | 0.60 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.60 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.60 |
| ▸ | STK16 | O75716 | 1/20 | 0.60 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.60 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.60 |
| ▸ | JAK1 | P23458 | 1/20 | 0.60 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264616 | 1.00 | PIK3CD (0.69) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL2397222 | 1.00 | PIK3CD (0.69) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL2395168 | 0.93 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL2396760 | 0.93 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL2395163 | 0.93 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL1497642 | 0.88 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL2399479 | 0.88 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL12264614 | 0.88 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL1497644 | 0.88 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 | |
| SCHEMBL1497546 | 0.87 | PIK3CD (0.71) | PIK3CDPIK3CAPIK3CBPIK3CGABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230476-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230476-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | PIK3CA, PIK3CB, PIK3C2B | PIK3CD 5/4885PIK3CA 1/4885PIK3CB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.