SCHEMBL2397256

SCHEMBL2397256

C=CC(=O)OS(=O)(=O)OC(=O)C=C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.39
ALDH1A1 P00352 6/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
FGFR4 P22455 1/20 0.33
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10777951 0.85 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4142643 0.85 TSHR (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL27900024 0.83 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8975780 0.80
SCHEMBL8498693 0.79 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27682293 0.79 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28384202 0.79 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1926035 0.78
SCHEMBL29216596 0.78
SCHEMBL8467035 0.78 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114634592-A Preparation method and application of acrylic acid high-initial-viscosity high-strength back adhesive emulsion 上海保立佳新材料有限公司 2022-06-17 CN claimed
CN-114617868-A NRF2 activating compounds and uses thereof 参宿七制药股份有限公司 2022-06-14 CN claimed
CN-112485442-A Small molecule target screening method based on chemical proteomics and application thereof 中国药科大学 2021-03-12 CN claimed
US-8026016-B2 Polymer electrolyte membrane and fuel cell employing the same SAMSUNG SDI CO., LTD. (KR) 2011-09-27 US claimed
EP-1630890-B1 Polymer electrolyte membrane and fuel cell employing the same SAMSUNG SDI CO LTD (KR) 2008-09-10 EP claimed
US-20060263659-A1 Polymer electrolyte membrane and fuel cell using the polymer electrolyte membrane SAMSUNG SDI CO. LTD. (KR) 2006-11-23 US claimed
US-20060046134-A1 Polymer electrolyte membrane and fuel cell employing the same SAMSUNG SDI CO., LTD. (KR) 2006-03-02 US claimed
EP-1630890-A1 Polymer electrolyte membrane and fuel cell employing the same Samsung SDI Co., Ltd. (KR) 2006-03-01 EP claimed
US-4259231-A ACRYLIC ISOCYANATE CURABLE WITH MOISTURE NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1981-03-31 US claimed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US disclosed
US-20260053943-A1 NANOCOMPOSITION COMPRISING ANTIBODY-DRUG CONJUGATE AND USE THEREOF FULGENT GENETICS INC (US) 2026-02-26 US disclosed
WO-2025064836-A2 AMINO ACID BINDING AGENTS AND THEIR USES GLYPHIC BIOTECHNOLOGIES, INC. (US) 2025-03-27 WO disclosed
WO-2024229100-A2 NANOCOMPOSITION COMPRISING ANTIBODY-DRUG CONJUGATE AND USE THEREOF ANP TECHNOLOGIES, INC. (US) 2024-11-07 WO disclosed
WO-2024077212-A2 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-11 WO disclosed
CN-1986613-A Polymer electrolyte membrane and fuel cell using the polymer electrolyte membrane SAMSUNG SDI CO LTD (KR) 2007-06-27 CN disclosed
US-20060263659-A1 Polymer electrolyte membrane and fuel cell using the polymer electrolyte membrane SAMSUNG SDI CO. LTD. (KR) 2006-11-23 US disclosed
US-20060046134-A1 Polymer electrolyte membrane and fuel cell employing the same SAMSUNG SDI CO., LTD. (KR) 2006-03-02 US disclosed
EP-1630890-A1 Polymer electrolyte membrane and fuel cell employing the same Samsung SDI Co., Ltd. (KR) 2006-03-01 EP disclosed
US-4465690-A ALGICIDES CHEVRON RESEARCH COMPANY (US) 1984-08-14 US disclosed
US-4259231-A ACRYLIC ISOCYANATE CURABLE WITH MOISTURE NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1981-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR TSHR 160/4885ALDH1A1 1062/4885TP53 2182/4885
US-20260053943-A1 NANOCOMPOSITION COMPRISING ANTIBODY-DRUG CONJUGATE AND USE THEREOF CD47, PBK, CD4 TSHR 622/4885ALDH1A1 1856/4885TP53 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.