SCHEMBL2397344

SCHEMBL2397344

[Ru].c1ccc(-c2cccnc2-c2cccnc2-c2ccccn2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
LMNA P02545 3/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
BLM P54132 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
PTPRC P08575 2/20 0.47
CTSL P07711 1/20 0.47
CTSS P25774 1/20 0.47
PTPN13 Q12923 1/20 0.47
TP53 P04637 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
NPC1 O15118 3/20 0.43
ALOX15 P16050 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30586095 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29648219 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31365059 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5595486 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31635941 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29539491 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29587096 0.96 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL78140 0.96 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL319436 0.96 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1504323 0.96 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110226325-A1 PHOTOELECTRIC CONVERSION DEVICE SONY CORPORATION (JP) 2011-09-22 US disclosed
EP-2367187-A2 Photoelectric conversion device Sony Corporation (JP) 2011-09-21 EP disclosed