Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 13/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21164443 | 0.81 | GBA1 (0.39) | GBA1HRH4HRH3CYP19A1 | |
| SCHEMBL20243620 | 0.81 | CYP19A1 (0.41) | GBA1HRH4HRH3CYP19A1 | |
| SCHEMBL1753962 | 0.80 | GBA1 (0.45) | GBA1HRH4HRH3CYP19A1 | |
| SCHEMBL12299387 | 0.79 | GBA1 (0.51) | GBA1HRH4HRH3 | |
| SCHEMBL12299383 | 0.79 | GBA1 (0.51) | GBA1HRH4HRH3 | |
| SCHEMBL3535989 | 0.77 | GBA1 (0.50) | GBA1HRH4HRH3CYP19A1 | |
| SCHEMBL16002534 | 0.77 | CYP19A1 (0.38) | GBA1HRH4HRH3CYP19A1 | |
| SCHEMBL12603039 | 0.77 | HRH4 (0.39) | GBA1HRH4HRH3CYP19A1 | |
| SCHEMBL255017 | 0.77 | GBA1 (0.41) | GBA1CYP19A1 | |
| SCHEMBL9285404 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222767-A1 | CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS | GLYCOMIMETICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |