Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 4/20 | 0.85 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.85 |
| ▸ | PGR | P06401 | 2/20 | 0.85 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.74 |
| ▸ | HSD11B2 | P80365 | 4/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medrysone SCHEMBL4493 | 0.92 | CYP3A4 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| Medrysone SCHEMBL12998543 | 0.92 | CYP3A4 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| Medrysone SCHEMBL3048275 | 0.92 | CYP3A4 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| Medrysone SCHEMBL13054978 | 0.92 | CYP3A4 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| Medrysone SCHEMBL29866793 | 0.92 | CYP3A4 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| Medrysone SCHEMBL840781 | 0.88 | CYP3A4 (0.93) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL20814164 | 0.85 | SERPINA6 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL19510152 | 0.85 | SERPINA6 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL13981876 | 0.85 | SERPINA6 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL15873848 | 0.85 | SERPINA6 (1.00) | CYP3A4HIF1ASMN1; SMN2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220061-A2 | HETERODIMER COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | RIPPLE THERAPEUTICS CORPORATION (CA) | 2021-11-04 | — | — | WO | disclosed |