Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23976383 | 0.88 | CLK2 (0.39) | CLK2LRRK2OGASYKIKBKE | |
| SCHEMBL23976962 | 0.82 | CLK2 (0.37) | CLK2LRRK2OGAIKBKETBK1 | |
| SCHEMBL30118737 | 0.80 | SYK (0.39) | SYK | |
| SCHEMBL23976000 | 0.80 | SYK (0.39) | SYK | |
| SCHEMBL30118642 | 0.76 | SYK (0.37) | SYK | |
| SCHEMBL23975987 | 0.76 | SYK (0.37) | SYK | |
| SCHEMBL30118793 | 0.75 | HDAC1 (0.37) | SYK | |
| SCHEMBL23976297 | 0.75 | HDAC1 (0.37) | SYK | |
| SCHEMBL23976206 | 0.75 | SYK (0.38) | SYK | |
| SCHEMBL30118609 | 0.75 | SYK (0.38) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222483-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |