⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706662 | 1.00 | — | — | |
| SCHEMBL18804327 | 0.80 | — | — | |
| SCHEMBL24002909 | 0.78 | — | — | |
| SCHEMBL23029904 | 0.74 | — | — | |
| SCHEMBL24064976 | 0.74 | — | — | |
| SCHEMBL19450825 | 0.73 | — | — | |
| SCHEMBL14540445 | 0.73 | — | — | |
| SCHEMBL16186891 | 0.73 | — | — | |
| SCHEMBL13057736 | 0.73 | — | — | |
| SCHEMBL18804399 | 0.72 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339183-B2 | Phosphate and phosphonate derivatives of 7-amino-5-thio-thiazolo[4,5-d]pyrimidines and their use in treating conditions associated with elevated levels of CX3CR1 and/or CX3CL1 | KANCERA AB (SE) | 2022-05-24 | — | — | US | disclosed |
| US-20210340167-A1 | PHOSPHATE AND PHOSPHONATE DERIVATIVES OF 7-AMINO-5-THIO-THIAZOLO[4,5-D]PYRIMIDINES AND THEIR USE IN TREATING CONDITIONS ASSOCIATED WITH ELEVATED LEVELS OF CX3CR1 AND/OR CX3CL1 | KANCERA AB (SE) | 2021-11-04 | — | — | US | disclosed |