SCHEMBL23977196

SCHEMBL23977196

CC1(CO)CCC(C)(c2ccc(O)cc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 7/20 0.41
ESR1 P03372 4/20 0.41
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
OPRD1 P41143 1/20 0.34
SCN10A Q9Y5Y9 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
GRM5 P41594 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21755391 0.93 ESR2 (0.40) ESR2ESR1MMP2MMP9OPRD1
SCHEMBL4492789 0.85 ESR2 (0.52) ESR2ESR1MMP2MMP9OPRD1
Phenol SCHEMBL4491407 0.78 CA12 (0.48) ESR2ESR1MMP2MMP9OPRD1
SCHEMBL1495106 0.77 ESR2 (0.54) ESR2ESR1MMP2MMP9OPRD1
SCHEMBL5241008 0.77 ESR2 (0.60) ESR2ESR1MMP2MMP9OPRD1
SCHEMBL1516123 0.75 ESR2 (0.61) ESR2ESR1MMP2MMP9OPRD1
SCHEMBL23977378 0.74 ESR2 (0.49) ESR2ESR1
SCHEMBL19486880 0.72 ESR2 (0.43) ESR2ESR1MMP2MMP9OPRD1
SCHEMBL3682201 0.72 ESR2 (0.39) ESR2ESR1MMP2MMP9OPRD1
SCHEMBL25276644 0.71 TSHR (0.39) SCN10AGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210340155-A1 Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation CU Ventures, Inc. 2021-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210340155-A1 Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation ESR2, GPER1, ESR1 ESR2 1/4885ESR1 3/4885MMP2 2716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.