SCHEMBL2397751

SCHEMBL2397751

Cc1cc(C)cc(CN2c3ccccc3C(C)(C)C23C=Nc2c(ccc4ccccc24)O3)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.65
THRB P10828 5/20 0.65
KDM4E B2RXH2 4/20 0.65
SMN1; SMN2 Q16637 4/20 0.65
ALOX12 P18054 2/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
PKM P14618 2/20 0.65
LMNA P02545 4/20 0.53
GAA P10253 4/20 0.53
RECQL P46063 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
ALDH1A1 P00352 2/20 0.53
HPGD P15428 2/20 0.53
HTT P42858 2/20 0.53
POLB P06746 1/20 0.53
MAPK1 P28482 1/20 0.53
NPSR1 Q6W5P4 3/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9747006 0.93 MAPT (0.63) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL9746036 0.91 MAPT (0.66) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL9746717 0.90 MAPT (0.65) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL2399622 0.90 MAPT (0.70) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL9746316 0.89 MAPT (0.66) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL2397282 0.87 MAPT (0.66) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL9745693 0.86 MAPT (0.65) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL2400708 0.86 MAPT (0.65) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL8525875 0.86 MAPT (0.62) MAPTTHRBKDM4ESMN1; SMN2ALOX12
SCHEMBL9746043 0.86 MAPT (0.62) MAPTTHRBKDM4ESMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10249693-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US disclosed
US-20150243933-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-27 US disclosed
US-20140231780-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-21 US disclosed
US-8729793-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2014-05-20 US disclosed
US-8508121-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2013-08-13 US disclosed
US-20110291552-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2011-12-01 US disclosed
US-20110228510-A1 OPTICAL FILTER AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-09-22 US disclosed
US-20080112049-A1 POLARIZER, POLARIZING PLATE, CIRCULAR POLARIZING FILTER, IMAGE DISPLAY SYSTEM, AND METHOD OF PRODUCING POLARIZER NITTO DENKO CORPORATION (JP) 2008-05-15 US disclosed
EP-1916097-A2 A non-glaring laminated body, a coated non-glaring laminated body, a non-glaring material, and a method for producing the non-glaring material MGC Filsheet Co., Ltd. (JP) 2008-04-30 EP disclosed
US-20080094704-A1 NON-GLARING LAMINATED BODY, A COATED NON-GLARING LAMINATED BODY, A NON-GLARING MATERIAL, AND A METHOD FOR PRODUCING THE NON-GLARING MATERIAL MGC FILSHEET CO., LTD. (JP) 2008-04-24 US disclosed
US-7118806-B2 Plastic molded product having photochromic characteristic and/or polarizing characteristics MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-10-10 US disclosed
US-6986946-B2 Transparent synthetic resin laminate having photochromism MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-01-17 US disclosed
US-6503965-B1 Ink composition comprising nonfluorescent pigment predispersed in alkyd resin, high boiling point hydrocarbon solvent, and stabilizer selected from antioxidants and antiskinning agents, which prevents alkyd resin from polymerizing BIC CORPORATION 2003-01-07 US disclosed
US-5208132-A Microencapsulation of hindered amines MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1993-05-04 US disclosed
EP-0171909-B1 SPIRO-OXAZINE COMPOUNDS AND PREPARATION THEREOF AND PHOTOCHROMIC SHAPED ARTICLE TORAY INDUSTRIES, INC. (JP) 1992-01-08 EP disclosed
US-4784474-A LENSES; WINDOWS TORAY INDUSTRIES, INC. (JP) 1988-11-15 US disclosed
EP-0171909-A1 Spiro-oxazine compounds and preparation thereof and photochromic shaped article TORAY INDUSTRIES, INC. (JP) 1986-02-19 EP disclosed