SCHEMBL23977984

SCHEMBL23977984

C#Cc1cc(F)c(F)c(/C(C)=N/OCc2c(C)cccc2/C(=C/CCC)C(=O)OC)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23965704 0.91
SCHEMBL23965695 0.86 HIF1A (0.33)
SCHEMBL23971763 0.84 HIF1A (0.39)
SCHEMBL23965592 0.84
SCHEMBL23965641 0.82
SCHEMBL23965636 0.82 GAA (0.34)
SCHEMBL23978207 0.81 SMN1; SMN2 (0.38)
SCHEMBL23971781 0.79 HIF1A (0.31)
SCHEMBL23978133 0.79 HPGD (0.39)
SCHEMBL23965635 0.79 KDM4E (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903581-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS I BASF SE (DE) 2021-11-03 EP disclosed