Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978280 | 0.78 | NR4A2 (0.66) | NR4A2MRGPRX4NR4A1NR4A3PTGER4 | |
| SCHEMBL23978010 | 0.76 | NR4A2 (0.60) | NR4A2MRGPRX4NR4A1NR4A3RXRA | |
| SCHEMBL23978219 | 0.76 | NR4A2 (0.60) | NR4A2MRGPRX4NR4A1NR4A3PTGER4 | |
| SCHEMBL23978033 | 0.76 | MRGPRX4 (0.69) | NR4A2MRGPRX4NR4A1NR4A3PTGER4 | |
| SCHEMBL23978233 | 0.73 | POLB (0.62) | NR4A2MRGPRX4NR4A1NR4A3MAOB | |
| SCHEMBL3980330 | 0.71 | NR4A2 (0.64) | NR4A2MRGPRX4NR4A1NR4A3PTGER4 | |
| SCHEMBL1369316 | 0.70 | NR4A2 (1.00) | NR4A2MRGPRX4NR4A1NR4A3RXRA | |
| SCHEMBL38659231 | 0.70 | NR4A2 (0.71) | NR4A2MRGPRX4NR4A1NR4A3RXRA | |
| SCHEMBL18687045 | 0.70 | NR4A2 (0.66) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL1177867 | 0.69 | NR4A2 (0.70) | NR4A2MRGPRX4NR4A1NR4A3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222174-A1 | BCL-2 INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2021-11-04 | — | — | WO | disclosed |