Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26494018 | 1.00 | USP2 (0.49) | USP2TAS1R3TAS1R1TAS1R2TSHR | |
| SCHEMBL30279430 | 1.00 | USP2 (0.49) | USP2TAS1R3TAS1R1TAS1R2TSHR | |
| SCHEMBL23978671 | 1.00 | USP2 (0.49) | USP2TAS1R3TAS1R1TAS1R2TSHR | |
| SCHEMBL23978988 | 0.90 | EPHX2 (0.46) | TAS1R3TAS1R1TAS1R2EPHX2HTT | |
| SCHEMBL30279441 | 0.90 | EPHX2 (0.46) | TAS1R3TAS1R1TAS1R2EPHX2HTT | |
| SCHEMBL23978569 | 0.90 | EPHX2 (0.46) | TAS1R3TAS1R1TAS1R2EPHX2HTT | |
| SCHEMBL26104441 | 0.90 | EPHX2 (0.46) | TAS1R3TAS1R1TAS1R2EPHX2HTT | |
| SCHEMBL30083836 | 0.90 | EPHX2 (0.46) | USP2TAS1R3TAS1R1TAS1R2TSHR | |
| SCHEMBL24803388 | 0.90 | EPHX2 (0.46) | USP2TAS1R3TAS1R1TAS1R2TSHR | |
| SCHEMBL26496578 | 0.90 | EPHX2 (0.46) | USP2TAS1R3TAS1R1TAS1R2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |