Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279395 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL26109531 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL23978998 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL23978563 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24803360 | 0.93 | EPHX2 (0.46) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30279401 | 0.93 | EPHX2 (0.46) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL26495115 | 0.93 | EPHX2 (0.46) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30279374 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24804476 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL23978594 | 0.92 | EPHX2 (0.41) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |