Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26495666 | 1.00 | EPHX2 (0.54) | EPHX2TSHRUSP2HTTKMT2A | |
| SCHEMBL30279330 | 1.00 | EPHX2 (0.54) | EPHX2TSHRUSP2HTTKMT2A | |
| SCHEMBL23978638 | 1.00 | EPHX2 (0.54) | EPHX2TSHRUSP2HTTKMT2A | |
| SCHEMBL21376866 | 1.00 | EPHX2 (0.54) | EPHX2TSHRUSP2HTTKMT2A | |
| SCHEMBL30083834 | 0.91 | HTT (0.54) | EPHX2TSHRUSP2HTTKMT2A | |
| SCHEMBL23978826 | 0.91 | HTT (0.54) | EPHX2TSHRUSP2HTTKMT2A | |
| SCHEMBL24804276 | 0.91 | HTT (0.54) | EPHX2TSHRUSP2HTTKMT2A | |
| SCHEMBL26506943 | 0.91 | HTT (0.54) | EPHX2TSHRUSP2HTTKMT2A | |
| SCHEMBL30279329 | 0.87 | EPHX2 (0.60) | EPHX2HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL24804265 | 0.87 | EPHX2 (0.60) | EPHX2HTTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |