Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.53 |
| ▸ | ITGAL | P20701 | 19/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978606 | 1.00 | ITGB2 (0.53) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL29019152 | 1.00 | ITGB2 (0.53) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL30279359 | 1.00 | ITGB2 (0.53) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL24803177 | 1.00 | ITGB2 (0.53) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL30083837 | 1.00 | ITGB2 (0.53) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL24804228 | 0.95 | ITGB2 (0.49) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL26105861 | 0.95 | ITGB2 (0.49) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL23978609 | 0.95 | ITGB2 (0.49) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL30279355 | 0.95 | ITGB2 (0.49) | ITGB2ICAM1ITGALTAS1R3TAS1R1 | |
| SCHEMBL24803375 | 0.90 | MAPT (0.48) | ITGB2ICAM1ITGALTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |