Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.37 |
| ▸ | ITGAL | P20701 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24803484 | 1.00 | EPHX2 (0.42) | EPHX2TAS1R3TAS1R1TAOK1TAOK3 | |
| SCHEMBL24804256 | 1.00 | EPHX2 (0.42) | EPHX2TAS1R3TAS1R1TAOK1TAOK3 | |
| SCHEMBL30083845 | 1.00 | EPHX2 (0.42) | EPHX2TAS1R3TAS1R1TAOK1TAOK3 | |
| SCHEMBL24805463 | 0.92 | EPHX2 (0.43) | EPHX2TAS1R3TAS1R1TAOK1TAOK3 | |
| SCHEMBL30083840 | 0.92 | EPHX2 (0.43) | EPHX2TAS1R3TAS1R1TAOK1TAOK3 | |
| SCHEMBL24803486 | 0.92 | EPHX2 (0.43) | EPHX2TAS1R3TAS1R1TAOK1TAOK3 | |
| SCHEMBL24805378 | 0.90 | ITGB2 (0.44) | EPHX2TAS1R3TAS1R1TAS1R2DHODH | |
| SCHEMBL23978610 | 0.90 | ITGB2 (0.44) | EPHX2TAS1R3TAS1R1TAS1R2DHODH | |
| SCHEMBL24804252 | 0.90 | EPHX2 (0.43) | EPHX2TAS1R3TAS1R1TAOK1TAOK3 | |
| SCHEMBL24805441 | 0.90 | EPHX2 (0.43) | EPHX2TAS1R3TAS1R1TAOK1TAOK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |