Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 16/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23980826 | 0.90 | GLP1R (0.60) | GLP1RGRM2 | |
| SCHEMBL23981035 | 0.88 | GLP1R (0.62) | GLP1R | |
| SCHEMBL31653407 | 0.88 | GLP1R (0.62) | GLP1R | |
| SCHEMBL23980851 | 0.88 | GLP1R (0.62) | GLP1R | |
| SCHEMBL23980929 | 0.87 | GLP1R (0.52) | GLP1RGRM2DRD4KDM4EOPRM1 | |
| SCHEMBL23980762 | 0.82 | GLP1R (0.51) | GLP1RGRM2 | |
| SCHEMBL23980908 | 0.80 | GLP1R (0.54) | GLP1RGRM2DRD4KDM4EOPRM1 | |
| SCHEMBL23980793 | 0.80 | GLP1R (0.63) | GLP1R | |
| SCHEMBL23980894 | 0.80 | GLP1R (0.63) | GLP1R | |
| SCHEMBL23980915 | 0.80 | GLP1R (0.46) | GLP1RGRM2DRD4KDM4EOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219019-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-11-04 | — | — | WO | disclosed |