Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 10/20 | 0.43 |
| ▸ | LTA4H | P09960 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23980868 | 0.92 | GLP1R (0.47) | KCNH2GLP1RLTA4HDRD2DRD3 | |
| SCHEMBL23981043 | 0.91 | GLP1R (0.45) | GLP1RLTA4H | |
| SCHEMBL23980950 | 0.91 | GLP1R (0.51) | GLP1RLTA4HDRD2DRD3 | |
| SCHEMBL23980923 | 0.91 | GLP1R (0.48) | KCNH2GLP1RLTA4HDRD2HTR2A | |
| SCHEMBL23980863 | 0.89 | KCNH2 (0.57) | KCNH2GLP1R | |
| SCHEMBL23980858 | 0.89 | KCNH2 (0.57) | KCNH2GLP1R | |
| SCHEMBL30275357 | 0.89 | KCNH2 (0.57) | KCNH2GLP1R | |
| SCHEMBL23981038 | 0.89 | KCNH2 (0.57) | KCNH2GLP1R | |
| SCHEMBL23980862 | 0.89 | KCNH2 (0.57) | KCNH2GLP1R | |
| SCHEMBL30275344 | 0.89 | KCNH2 (0.57) | KCNH2GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219019-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-11-04 | — | — | WO | disclosed |