SCHEMBL23986325 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	DDB1	Q16531	19/20	0.49

▸	CRBN	Q96SW2	19/20	0.49

▸	IKZF3	Q9UKT9	2/20	0.40

▸	ALDH1A1	P00352	1/20	0.40

▸	CHRM2	P08172	1/20	0.40

▸	OPRM1	P35372	1/20	0.40

▸	CYP1A2	P05177	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	TDP1	Q9NUW8	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23845092	0.92	CRBN (0.52)	DDB1CRBNIKZF3ALDH1A1CHRM2
SCHEMBL22527240	0.92	CRBN (0.52)	DDB1CRBNIKZF3ALDH1A1CHRM2
SCHEMBL22856248	0.92	CRBN (0.52)	DDB1CRBNIKZF3ALDH1A1CHRM2
SCHEMBL22512333	0.87	DDB1 (0.49)	DDB1CRBNIKZF3ALDH1A1CHRM2
SCHEMBL29236448	0.86	DDB1 (0.54)	DDB1CRBNIKZF3ALDH1A1CHRM2
SCHEMBL24132325	0.86	DDB1 (0.48)	DDB1CRBNIKZF3ALDH1A1CHRM2
SCHEMBL30258439	0.85	CRBN (0.46)	DDB1CRBNIKZF3ALDH1A1CHRM2
SCHEMBL26044487	0.85	CRBN (0.42)	DDB1CRBN
SCHEMBL24204700	0.84	CRBN (0.49)	DDB1CRBNIKZF3ALDH1A1CHRM2
SCHEMBL30258476	0.83	CRBN (0.44)	DDB1CRBNIKZF3ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021222114-A1	BCL-2 PROTEIN INHIBITORS	RECURIUM IP HOLDINGS, LLC (US)	2021-11-04	—	—	WO	disclosed