Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA6 | P23280 | 5/20 | 0.56 |
| ▸ | CA7 | P43166 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA4 | P22748 | 4/20 | 0.53 |
| ▸ | CA5A | P35218 | 4/20 | 0.53 |
| ▸ | CA3 | P07451 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1451831 | 1.00 | CA12 (0.56) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL725777 | 1.00 | CA12 (0.56) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL2377223 | 1.00 | CA12 (0.56) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL1565417 | 0.97 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL9100273 | 0.97 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL27525013 | 0.97 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL863599 | 0.97 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL3657736 | 0.97 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL9716193 | 0.97 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL18288 | 0.97 | CA12 (0.59) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2127741-B1 | WATER ABSORBENT AND PROCESS FOR PRODUCING THE SAME | NIPPON CATALYTIC CHEM IND (JP) | 2019-05-15 | — | — | EP | disclosed |
| EP-2185631-B1 | BINDING METHOD OF WATER ABSORBENT RESIN | NIPPON CATALYTIC CHEM IND (JP) | 2017-01-18 | — | — | EP | disclosed |
| EP-1683813-B1 | PRODUCTION METHOD OF WATER-ABSORBENT RESIN | NIPPON CATALYTIC CHEM IND (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-8846823-B2 | Water absorbing agent and production method thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2014-09-30 | — | — | US | disclosed |
| US-8598254-B2 | Binding method of water absorbent resin | NIPPON SHOKUBAI CO., LTD. (JP) | 2013-12-03 | — | — | US | disclosed |
| US-8513364-B2 | Production method of water-absorbent resin | NIPPON SHOKUBAI CO., LTD. (JP) | 2013-08-20 | — | — | US | disclosed |
| EP-2125916-B1 | WATER ABSORBENT RESIN PRODUCTION METHOD AND USAGE THEREOF | NIPPON CATALYTIC CHEM IND (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-8252715-B2 | Water-absorbing agent and production method thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2012-08-28 | — | — | US | disclosed |
| US-8044157-B2 | Water absorbent resin production method and usage thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20110237739-A1 | Binding method of water absorbent resin | NIPPON SHOKUBAI CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| WO-2008114847-A1 | WATER ABSORBENT RESIN PRODUCTION METHOD AND USAGE THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2008-09-25 | — | — | WO | disclosed |
| US-20080221229-A1 | Surface crosslinking of water absorbent resin particle after mixing with a compound with a reactive or hydrophobic group; neutralization; centrifugal retention capacity, saline flow conductivity; disposable sanitary napkins, incontinence pads, diapers | NIPPON SHOKUBAI CO., LTD. (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1765913-B1 | WATER ABSORBING AGENT AND PRODUCTION METHOD THEREOF | NIPPON CATALYTIC CHEM IND (JP) | 2008-08-27 | — | — | EP | disclosed |
| US-20080032888-A1 | Water Absorbing Agent and Production Method Thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2008-02-07 | — | — | US | disclosed |
| EP-1765913-A1 | WATER ABSORBING AGENT AND PRODUCTION METHOD THEREOF | Nippon Shokubai Co.,Ltd. (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20060167198-A1 | Production method of water-absorbent resin | NIPPON SHOKUBAI CO., LTD. | 2006-07-27 | — | — | US | disclosed |
| EP-1683813-A2 | Production method of water-absorbent resin | Nippon Shokubai Co.,Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |
| EP-1616581-A1 | Water absorbent resin composition and production method thereof | Nippon Shokubai Co., Ltd. (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-20050288182-A1 | Water absorbent resin composition and production method thereof | NIPPON SHOKUBAI CO., LTD (JP) | 2005-12-29 | — | — | US | disclosed |
| WO-2005108472-A1 | WATER ABSORBING AGENT AND PRODUCTION METHOD THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2005-11-17 | — | — | WO | disclosed |