Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514507 | 0.70 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL4507846 | 0.59 | KDM4E (0.36) | — | |
| SCHEMBL6272478 | 0.55 | — | — | |
| SCHEMBL12992748 | 0.35 | — | — | |
| SCHEMBL10066089 | 0.32 | — | — | |
| SCHEMBL10784011 | 0.32 | — | — | |
| SCHEMBL13719381 | 0.32 | — | — | |
| Methane SCHEMBL23044967 | 0.26 | — | — | |
| SCHEMBL714322 | 0.26 | — | — | |
| SCHEMBL11115109 | 0.26 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680964-B1 | PYRROLO [3,2-e]INDOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE | UNIV SANTIAGO COMPOSTELA (ES) | 2002-01-16 | — | — | EP | claimed |
| EP-0680964-A1 | NEW PIRROLO 3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-11-08 | — | — | EP | claimed |
| WO-1995014022-A1 | NEW PIRROLO [3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-05-26 | — | — | WO | claimed |
| US-8017640-B2 | Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment | UNIVERSITY OF BRADFORD (GB) | 2011-09-13 | — | — | US | disclosed |
| US-7626026-B2 | Pyrrolo-indole and pyrrolo-quinoline derivatives as prodrugs for tumour treatment | UNIVERSITY OF BRADFORD (GB) | 2009-12-01 | — | — | US | disclosed |
| EP-1409480-B1 | PYRROLO-INDOLE AND PYRROLO-QUINOLINE DERIVATIVES AS PRODRUGS FOR TUMOUR TREATMENT | UNIV LONDON PHARMACY (GB) | 2007-11-14 | — | — | EP | disclosed |
| US-20070161669-A1 | Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment | SCHOOL OF PHARMACY UNIVERSITY OF LONDON | 2007-07-12 | — | — | US | disclosed |
| EP-1408970-B1 | INDOLINES AND TETRAHYDRO-QUINOLINES AS PRODRUGS FOR TUMOUR TREATMENT | UNIV LONDON PHARMACY (GB) | 2007-05-09 | — | — | EP | disclosed |
| US-7192977-B2 | Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment | SCHOOL OF PHARMACY (GB) | 2007-03-20 | — | — | US | disclosed |
| US-7179921-B2 | Indoline and tetrahydro-quinolines as prodrugs for tumour treatment | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2007-02-20 | — | — | US | disclosed |
| EP-1408960-B1 | BENZ-INDOLE AND BENZO-QUINOLINE DERIVATIVES AS PRODRUGS FOR TUMOUR TREATMENT | UNIV LONDON PHARMACY (GB) | 2006-05-31 | — | — | EP | disclosed |
| EP-1408970-A1 | INDOLINES AND TETRAHYDRO-QUINOLINES AS PRODRUGS FOR TUMOUR TREATMENT | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002067937-A1 | INDOLINE AND TETRAHYDRO-QUINOLINES AS PRODRUGS FOR TUMOUR TREATMENT | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002068412-A1 | PYRROLO-INDOLE AND PYRROLO-QUINOLINE DERIVATIVES AS PRODRUGS FOR TUMOUR TREATMENT | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002067930-A1 | BENZ-INDOLE AND BENZO-QUINOLINE DERIVATIVES AS PRODRUGS FOR TUMOR TREATMENT | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2002-09-06 | — | — | WO | disclosed |
| EP-0680964-B1 | PYRROLO [3,2-e]INDOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE | UNIV SANTIAGO COMPOSTELA (ES) | 2002-01-16 | — | — | EP | disclosed |
| US-6130237-A | Condensed N-aclyindoles as antitumor agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-10-10 | — | — | US | disclosed |
| EP-0680964-A1 | NEW PIRROLO 3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-11-08 | — | — | EP | disclosed |
| WO-1995014022-A1 | NEW PIRROLO [3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-05-26 | — | — | WO | disclosed |
| US-4916217-A | Phosphorus containing derivatives of epipodophyllotoxin | BRISTOL-MYERS COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161669-A1 | Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment | CYP1B1, CYP1A1, RECQL | CYP19A1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.