Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666053 | 0.90 | APP (0.50) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL11236423 | 0.86 | APP (0.39) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL30949857 | 0.85 | EPHX2 (0.44) | APPEPHX2 | |
| SCHEMBL30949863 | 0.85 | EPHX2 (0.44) | APPEPHX2 | |
| SCHEMBL30949869 | 0.85 | EPHX2 (0.44) | APPEPHX2 | |
| SCHEMBL8816521 | 0.85 | EPHX2 (0.44) | APPEPHX2 | |
| SCHEMBL16316707 | 0.85 | EPHX2 (0.44) | APPEPHX2 | |
| SCHEMBL30949867 | 0.85 | EPHX2 (0.44) | APPEPHX2 | |
| SCHEMBL23988450 | 0.84 | APP (0.34) | APPEPHX2 | |
| SCHEMBL11238895 | 0.84 | APP (0.41) | APPPTGS1PDE4ALMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340404-A1 | SILANOL COMPOSITIONS AND METHODS OF USE | 3M INNOVATIVE PROPERTIES COMPANY | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340404-A1 | SILANOL COMPOSITIONS AND METHODS OF USE | EPCAM, ITGA8, CD99 | APP 3050/4885PTGS1 1045/4885PDE4A 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.