Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988718 | 1.00 | KMT2A (0.50) | KMT2AMEN1JAK2HDAC8CYP17A1 | |
| SCHEMBL23964045 | 0.97 | KMT2A (0.52) | KMT2AMEN1JAK2HDAC8CYP17A1 | |
| SCHEMBL18975494 | 0.97 | KMT2A (0.52) | KMT2AMEN1JAK2HDAC8CYP17A1 | |
| SCHEMBL25993767 | 0.90 | MEN1 (0.56) | KMT2AMEN1CTSSCTSKPTPRB | |
| SCHEMBL19391314 | 0.90 | MEN1 (0.56) | KMT2AMEN1CTSSCTSKPTPRB | |
| SCHEMBL22815478 | 0.90 | MEN1 (0.56) | KMT2AMEN1CTSSCTSKPTPRB | |
| SCHEMBL19277932 | 0.90 | MEN1 (0.56) | KMT2AMEN1CTSSCTSKPTPRB | |
| SCHEMBL19391315 | 0.90 | MEN1 (0.56) | KMT2AMEN1CTSSCTSKPTPRB | |
| SCHEMBL27103092 | 0.87 | KMT2A (0.62) | KMT2AMEN1JAK2HDAC8CYP17A1 | |
| SCHEMBL25932908 | 0.86 | KMT2A (0.51) | KMT2AMEN1JAK2HDAC8CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216572-A1 | LIPID COMPOSITIONS FOR DELIVERY OF STING AGONIST COMPOUNDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-10-28 | — | — | WO | disclosed |