Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27534430 | 0.96 | SLC6A2 (0.49) | SLC6A2SLC6A4NOS2NOS3NOS1 | |
| SCHEMBL30859681 | 0.94 | SLC6A2 (0.48) | SLC6A2SLC6A4NOS2GNAI3GNAO1 | |
| SCHEMBL5868706 | 0.90 | SLC6A2 (0.54) | SLC6A2SLC6A4NOS2NOS3NOS1 | |
| SCHEMBL1206196 | 0.90 | SLC6A2 (0.51) | SLC6A2SLC6A4NOS2NOS3NOS1 | |
| SCHEMBL8851211 | 0.85 | SLC6A4 (0.43) | SLC6A2SLC6A4NOS2NOS3NOS1 | |
| SCHEMBL8851948 | 0.85 | SLC6A2 (0.43) | SLC6A2SLC6A4NOS2NOS3NOS1 | |
| SCHEMBL8851594 | 0.85 | SLC6A2 (0.43) | SLC6A2SLC6A4NOS2NOS3NOS1 | |
| SCHEMBL8852104 | 0.84 | SLC6A2 (0.43) | SLC6A2SLC6A4NOS2NOS3NOS1 | |
| SCHEMBL13885993 | 0.82 | SLC6A2 (0.51) | SLC6A2SLC6A4NOS2NOS3NOS1 | |
| SCHEMBL8851454 | 0.82 | SLC6A2 (0.42) | SLC6A2SLC6A4NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222875-A1 | METHODS OF USING ALK2 INHIBITORS | KEROS THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |