Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.41 |
| ▸ | FLT1 | P17948 | 4/20 | 0.41 |
| ▸ | FLT4 | P35916 | 3/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | BMP4 | P12644 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988897 | 0.87 | KDR (0.51) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL26867392 | 0.87 | AVPR1B (0.42) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL24409810 | 0.86 | KDR (0.40) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL17441669 | 0.86 | AVPR1B (0.42) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL17442277 | 0.86 | AVPR1B (0.42) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL17442353 | 0.85 | ACVR1 (0.51) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL26867402 | 0.82 | AVPR1B (0.44) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL26867406 | 0.81 | KDR (0.43) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL24409705 | 0.81 | KDR (0.42) | KDRFLT1FLT4PRKAB1PRKAB2 | |
| SCHEMBL17442159 | 0.81 | AVPR1B (0.44) | KDRFLT1FLT4PRKAB1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222875-A1 | METHODS OF USING ALK2 INHIBITORS | KEROS THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |