⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13975739 | 1.00 | — | — | |
| SCHEMBL24355710 | 0.72 | TSHR (0.41) | — | |
| SCHEMBL2850539 | 0.71 | — | — | |
| SCHEMBL1988778 | 0.71 | — | — | |
| SCHEMBL5353428 | 0.71 | — | — | |
| SCHEMBL2914504 | 0.71 | — | — | |
| SCHEMBL8021749 | 0.71 | — | — | |
| SCHEMBL14435768 | 0.69 | — | — | |
| SCHEMBL7045750 | 0.69 | — | — | |
| SCHEMBL1498076 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220433-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220435-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023212239-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023212231-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| US-9245290-B2 | Caspase inhibitors and uses thereof | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2016-01-26 | — | — | US | disclosed |
| US-20140011847-A1 | CASPASE INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-09 | — | — | US | disclosed |
| US-8518942-B2 | Caspase inhibitors and uses thereof | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2013-08-27 | — | — | US | disclosed |
| US-20110230527-A1 | CASPASE INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-09-22 | — | — | US | disclosed |
| WO-2010017408-A1 | CASPASE INHIBITORS AND USES THEREOF | THE BUCK INSTITUTE FOR AGE RESEARCH (US) | 2010-02-11 | — | — | WO | disclosed |