Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257220 | 0.85 | TDP1 (0.41) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL27257219 | 0.85 | TDP1 (0.41) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL1294979 | 0.85 | TDP1 (0.45) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL1295600 | 0.85 | TDP1 (0.45) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL1295598 | 0.85 | TDP1 (0.45) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL1295805 | 0.83 | TDP1 (0.40) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL1295806 | 0.83 | TDP1 (0.40) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL1295257 | 0.83 | TDP1 (0.40) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL27257147 | 0.83 | TDP1 (0.40) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL27257146 | 0.83 | TDP1 (0.40) | MAOBMAOATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |