Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 5/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23995439 | 1.00 | NT5E (0.43) | NT5ERAF1 | |
| SCHEMBL23993689 | 0.92 | NT5E (0.44) | NT5ERAF1 | |
| SCHEMBL23994333 | 0.92 | NT5E (0.44) | NT5ERAF1 | |
| SCHEMBL23995432 | 0.88 | NT5E (0.44) | NT5ERAF1 | |
| SCHEMBL23993723 | 0.88 | NT5E (0.44) | NT5ERAF1 | |
| SCHEMBL24514825 | 0.88 | NT5E (0.44) | NT5ERAF1 | |
| SCHEMBL25004690 | 0.86 | NT5E (0.47) | NT5E | |
| SCHEMBL23994346 | 0.84 | NT5E (0.46) | NT5E | |
| SCHEMBL24514930 | 0.84 | NT5E (0.62) | NT5E | |
| SCHEMBL24515119 | 0.83 | NT5E (0.44) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |