Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 8/20 | 0.38 |
| ▸ | RAF1 | P04049 | 5/20 | 0.33 |
| ▸ | BRAF | P15056 | 5/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993042 | 1.00 | NT5E (0.38) | NT5ERAF1BRAFCDC7DBF4 | |
| SCHEMBL23993052 | 1.00 | NT5E (0.38) | NT5ERAF1BRAFCDC7DBF4 | |
| SCHEMBL23994992 | 0.88 | NT5E (0.35) | NT5ERAF1BRAFCDC7DBF4 | |
| SCHEMBL23993811 | 0.88 | NT5E (0.35) | NT5ERAF1BRAFCDC7DBF4 | |
| SCHEMBL23993812 | 0.88 | NT5E (0.35) | NT5ERAF1BRAFCDC7DBF4 | |
| SCHEMBL23993293 | 0.87 | NT5E (0.41) | NT5ERAF1BRAF | |
| SCHEMBL23993304 | 0.87 | NT5E (0.41) | NT5ERAF1BRAF | |
| SCHEMBL23994997 | 0.87 | NT5E (0.41) | NT5ERAF1BRAF | |
| SCHEMBL23994437 | 0.86 | NT5E (0.38) | NT5ERAF1BRAF | |
| SCHEMBL25004243 | 0.86 | NT5E (0.38) | NT5ERAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |