Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.35 |
| ▸ | NT5E | P21589 | 6/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993814 | 0.87 | NT5E (0.35) | MAPTKDM4CNT5E | |
| SCHEMBL23993071 | 0.87 | NT5E (0.33) | NT5E | |
| SCHEMBL25004807 | 0.87 | NT5E (0.34) | MAPTKDM4CNT5E | |
| SCHEMBL23993286 | 0.86 | JAK2 (0.33) | MAPTKDM4CNT5E | |
| SCHEMBL28947404 | 0.84 | NT5E (0.32) | NT5E | |
| SCHEMBL23994859 | 0.84 | NT5E (0.32) | NT5E | |
| SCHEMBL23995011 | 0.83 | NT5E (0.36) | NT5E | |
| SCHEMBL23993714 | 0.81 | NT5E (0.32) | NT5E | |
| SCHEMBL23993340 | 0.81 | NT5E (0.38) | NT5E | |
| SCHEMBL23994621 | 0.81 | NT5E (0.38) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |