Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25731885 | 0.82 | CHRM5 (0.66) | CHRM5TAAR1NPC1RAB9AMAPT | |
| SCHEMBL25731888 | 0.80 | CHRM5 (0.68) | CHRM5TAAR1NPC1RAB9AMAPT | |
| SCHEMBL23996044 | 0.79 | GFER (0.58) | NPC1RAB9AMAPTALDH1A1NPSR1 | |
| SCHEMBL27885399 | 0.76 | CHRM5 (0.72) | CHRM5TAAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL31182402 | 0.76 | CHRM5 (0.72) | CHRM5TAAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL14950238 | 0.76 | CHRM5 (0.72) | CHRM5TAAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL23732607 | 0.76 | CHRM5 (0.62) | CHRM5TAAR1NPC1RAB9AMAPT | |
| SCHEMBL7747064 | 0.76 | TAAR1 (0.58) | CHRM5TAAR1NPC1RAB9AMAPT | |
| SCHEMBL17560805 | 0.76 | NPC1 (0.65) | CHRM5TAAR1NPC1RAB9AMAPT | |
| SCHEMBL7747066 | 0.76 | TAAR1 (0.58) | CHRM5TAAR1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166464-B2 | Self-assembled active agents | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2021-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166464-B2 | Self-assembled active agents | PCNA, POLM, MUS81 | CHRM5 4294/4885TAAR1 3783/4885NPC1 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.