Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997330 | 0.84 | KMT2A (0.53) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL30336785 | 0.84 | KMT2A (0.53) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL23997395 | 0.83 | MEN1 (0.59) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL30336707 | 0.83 | MEN1 (0.59) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL28492451 | 0.82 | MEN1 (0.56) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL31362216 | 0.80 | MEN1 (0.56) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL28357637 | 0.78 | MEN1 (0.51) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL25234619 | 0.78 | MEN1 (0.54) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL25238726 | 0.77 | MEN1 (0.56) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL25229540 | 0.77 | MEN1 (0.52) | MEN1KMT2AGAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226003-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-11-11 | — | — | WO | disclosed |