⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28876362 | 1.00 | — | — | |
| SCHEMBL23999920 | 1.00 | — | — | |
| SCHEMBL2302961 | 0.72 | — | — | |
| SCHEMBL12477 | 0.72 | — | — | |
| SCHEMBL7920447 | 0.72 | — | — | |
| SCHEMBL11895879 | 0.72 | — | — | |
| SCHEMBL25112161 | 0.71 | CYP2D6 (0.31) | — | |
| SCHEMBL26308822 | 0.71 | CYP2D6 (0.31) | — | |
| SCHEMBL15038190 | 0.71 | CYP2D6 (0.31) | — | |
| SCHEMBL19495790 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021226477-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021226458-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |